| Rank | Name | Pos | Team | Salary Diff |
| 1 | Chase Utley | 2B | PHI | $-31 |
| 2 | Zack Greinke | P | KC | $-27 |
| 3 | Dan Haren | P | LAA | $-26 |
| 4 | Javier Vazquez | P | NYY | $-24 |
| 5 | Jacoby Ellsbury | OF | BOS | $-24 |
| 6 | Tim Lincecum | P | SF | $-24 |
| 7 | Brian Roberts | 2B | BAL | $-22 |
| 8 | Grady Sizemore | OF | CLE | $-22 |
| 9 | Jake Peavy | P | CHW | $-21 |
| 10 | Pablo Sandoval | 3B/1B | SF | $-21 |
| 11 | Manny Ramirez | OF | CHW | $-20 |
| 12 | Jair Jurrjens | P | ATL | $-20 |
| 13 | Tommy Hanson | P | ATL | $-19 |
| 14 | Nate McLouth | OF | ATL | $-19 |
| 15 | Jason Bay | OF | NYM | $-19 |
| 16 | Trevor Hoffman | P | MIL | $-19 |
| 17 | Josh Beckett | P | BOS | $-19 |
| 18 | Chipper Jones | 3B | ATL | $-19 |
| 19 | Lance Berkman | 1B | NYY | $-18 |
| 20 | Miguel Tejada | 3B/SS | SD | $-18 |
| 21 | Francisco Rodriguez | P | NYM | $-18 |
| 22 | Kendry Morales | 1B | LAA | $-18 |
| 23 | Jason Kubel | DH/OF | MIN | $-17 |
| 24 | Mike Gonzalez | P | BAL | $-17 |
| 25 | John Lackey | P | BOS | $-16 |
| 26 | Brad Hawpe | OF | TB | $-16 |
| 27 | Randy Wells | P | CHC | $-16 |
| 28 | Andrew Bailey | P | OAK | $-16 |
| 29 | Julio Borbon | DH/OF | TEX | $-15 |
| 30 | Rich Harden | P | TEX | $-15 |
| 31 | Mike Cameron | OF | BOS | $-15 |
| 32 | Randy Winn | OF | STL | $-15 |
| 33 | Alex Rodriguez | 3B | NYY | $-15 |
| 34 | Mike Lowell | 3B | BOS | $-15 |
| 35 | Carlos Beltran | OF | NYM | $-15 |
| 36 | Bengie Molina | C | TEX | $-15 |
| 37 | Carlos Lee | OF | HOU | $-14 |
| 38 | A.J. Burnett | P | NYY | $-14 |
| 39 | Matt Kemp | OF | LAD | $-14 |
| 40 | Huston Street | P | COL | $-14 |
| 41 | James Shields | P | TB | $-13 |
| 42 | Nick Markakis | OF | BAL | $-13 |
| 43 | Mark DeRosa | 3B/OF | SF | $-13 |
| 44 | Johnny Damon | OF | DET | $-13 |
| 45 | Raul Ibanez | OF | PHI | $-13 |
| 46 | Jimmy Rollins | SS | PHI | $-13 |
| 47 | Jose Lopez | 2B/3B | SEA | $-13 |
| 48 | Jason Bartlett | SS | TB | $-13 |
| 49 | Jorge Cantu | 1B/3B | TEX | $-12 |
| 50 | Milton Bradley | OF | SEA | $-12 |