Derek Lowe| Year | W | L | Sv | Hold | IP | H | BB | SO | ER | ERA | WHIP | Rate |
| 2013 | 1 | 0 | 0 | 0 | 13.0 | 16 | 3 | 8 | 13 | 9.00 | 1.462 | -7.9 |
| 2012 | 9 | 11 | 1 | 0 | 142.7 | 180 | 51 | 55 | 81 | 5.11 | 1.619 | -9.1 |
| 2011 | 9 | 17 | 0 | 0 | 187.0 | 212 | 70 | 137 | 105 | 5.05 | 1.508 | -4.8 |
| 2010 | 15 | 12 | 0 | 0 | 188.7 | 199 | 57 | 131 | 84 | 4.01 | 1.357 | 35.7 |
| 2009 | 15 | 10 | 0 | 0 | 194.7 | 232 | 63 | 111 | 101 | 4.67 | 1.515 | 10.3 |
| 2008 | 14 | 11 | 0 | 0 | 211.0 | 194 | 45 | 147 | 76 | 3.24 | 1.133 | 67.9 |
| 2007 | 12 | 14 | 0 | 0 | 193.3 | 189 | 54 | 142 | 83 | 3.86 | 1.257 | 41.7 |
| 2006 | 16 | 8 | 0 | 0 | 218.0 | 221 | 55 | 123 | 88 | 3.63 | 1.266 | 44.3 |
| 2005 | 12 | 15 | 0 | 0 | 222.0 | 223 | 55 | 146 | 89 | 3.61 | 1.252 | 44.2 |
| 2004 | 14 | 12 | 0 | 0 | 182.7 | 224 | 71 | 105 | 110 | 5.42 | 1.615 | -19.5 |
| 2003 | 17 | 7 | 0 | 0 | 203.3 | 216 | 72 | 110 | 101 | 4.47 | 1.416 | 18.0 |
| 2002 | 21 | 8 | 0 | 0 | 219.7 | 166 | 48 | 127 | 63 | 2.58 | 0.974 | 83.2 |
| 2001 | 5 | 10 | 24 | 0 | 91.7 | 103 | 29 | 82 | 36 | 3.53 | 1.440 | 32.7 |
| 2000 | 4 | 4 | 42 | 0 | 91.3 | 90 | 22 | 79 | 26 | 2.56 | 1.226 | 60.0 |
| 1999 | 6 | 3 | 15 | 0 | 109.3 | 84 | 25 | 80 | 32 | 2.63 | 0.997 | 49.7 |
| 1998 | 3 | 9 | 4 | 0 | 123.0 | 126 | 42 | 77 | 55 | 4.02 | 1.366 | 11.7 |
| 1997 | 2 | 6 | 0 | 0 | 69.0 | 74 | 23 | 52 | 47 | 6.13 | 1.406 | -14.3 |
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